topoisomerase i meaning in Chinese
《英文msh词典》Topoisomerase I
[入口词] Topoisomerase I
[主题词] DNA Topoisomerases,Type I
[英文释义] DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA,passage of the unbroken strand through the break,and rejoining of the broken strand. DNA Topoisomerases,Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
Examples
- the orf1 proteins of all four chinese senv isolates had two motifs ( ftl and yxxk ) which were conserved in replication-associated proteins . in all four chinese senv isolates, the putative non-structure orf2 protein had a cav-like region . the putative orf3 protein had a serine-rich tract preceded by a cluster of basic amino acids ( r and k ) . database scaning suggested this region had high a percentage of homology with dna topoisomerase i protein of d . melanogaster, and might play an important role in the replication of such single-stranded dna viruses
所有这四个中国分离株，均保留了o即1中与复制有关的保守序列(ftl和yxxk):在推测是非结构蛋白的orfz中均含有cav样保守区w‘x7一h一x3一c一xl一c一xs一h;orf3蛋白的碱性氨基酸(精氨酸和赖氨酸)簇后紧接着一个富含丝氨酸的区域，与d.molanogaster的dna拓扑异构酶i有一定的同源性，推测在单链dna的复制中起作用。